The current scenario shows a greater participation of women in the economy of entrepreneurship and innovation. This requires constant intervention and support to enhance and take advantage of the great skills, creativity, ideas and knowledge of women entrepreneurs, integrating strategies linked to digital transformation and environmental sustainability. The IELSM Creative Spark in Latin America represents a unique opportunity for female entrepreneurship to connect academia with business and entrepreneurship. Women entrepreneurs will be able to learn about new international approaches to readapting their business models and will have the opportunity to share their experiences and successes with international experts, academics and businessmen and women. Within Creative Spark, women entrepreneurs will have the opportunity to participate in: Creative Spark Entrepreneurial Business Workshops, World Café with Women Entrepreneurs, Business and Entrepreneurship Networking. In addition, attendees will have the opportunity to be part of one of the ten best and most diverse digital platforms for entrepreneurship in Germany, the IELSM platform, where they could participate after the Creative Spark and internationally accelerate their business model.